Call for applications: "Grand prix scientifique 2018" Simone and Cino Del Duca Foundation
Deadline: January 12th, 2018
Every year, alternatively under the disciplines of the two divisions of Academy of Sciences, the Simone and Cino Del Duca Foundation of the Institut de France awards a scientific prize based on the recommendations of a jury of members of the Institut de France.The Grand Prix will be awarded to a French or European scientist and his/her team that will propose an ambitious research project on promising theme.
In 2018, the Prize topic is : Mechanisms of resistance and adaptation to stress
Every living cell is submitted to numerous stresses (thermal, hydric, chemical, nutritional, infectious, pathological, radiological, metabolic, etc.) from its environment or genetic changes, creating situations that can put in danger its well-being and even its existence. Biological evolution has selected those cells that developed mechanisms of resistance and adaptation to these natural stresses or to xenobiotics like the pesticides and, during medical treatment, for example to antibiotics or chemotherapy. Our knowledge of these mechanisms at the molecular level recently progressed in a spectacular way. We can mention, for example, the adaptation to oxidizing stress with the central role of the Nrf2 pathway, the resistance to xenobiotics and to electrophilic stress with the key roles of the glutathione transferases and peroxidases, or the mechanisms of repair of the genetic material during a replicative or mutational stress.
The Simone and Cino Del Duca 2018 Prize will reward work in the field of resistance mechanisms and stress adaptation, which can cover all types of organisms and every biological situation.
The prize is as follows:
a) 200,000 € to finance the work of the award-winning group,
b) 25,000 € awarded to the director of the research group,
c) 50,000 € (maximum amount paid upon presentation of supporting documents) towards the hiring of one French or foreign postdoctoral researcher to be selected by the group director, in the two years following the award of the prize. An activity report must be sent within two months after the end of the contract. An agreement will be established between the laboratory and the Del Duca Foundation to define the conditions of payment.